The response of chronic lymphocytic leukemia to treatment by extracorporeal irradiation of the blood, assessed by isotope-labeling procedures.

cytes concerned,’4 and by the variety of behavior patterns displayednotably in regard to progression of the disease and response to therapy. This diversity is also reflected in the response shown by patients with CLL to treatment by extracorporeal irradiation of the blood ( ECIB). Patients so far treated by this technic at the Royal Marsden Hospital inelude nine with various forms of lymphoma. Preliminary reports on the hematologic response and reduction in lymph node size achieved,5 as well as on studies of lymphocyte kinetics based on the analysis of radiation-induced